Hemp-derived THC is delta-9-tetrahydrocannabinol sourced from the hemp plant, containing no more than 0.3% THC by dry weight. It's legal due to the 2018 U.S. Farm Bill, which distinguishes hemp from marijuana and permits the cultivation and sale of hemp-derived products, including those with minimal THC, for industrial and medicinal purposes.

Popular hemp-derived THC includes the molecule Delta-8-THC, another cannabinoid found in the cannabis plant, which is reported to have psychoactive effects, though milder compared to delta-9-THC found in marijuana. Users suggest that delta-8-THC can induce a more clear-headed high with less anxiety and paranoia. It may also provide relaxation, euphoria, and relief from certain symptoms such as nausea and pain. However, individual responses can vary.